Birinapant (TL32711)

Catalog No.: A12738
XIAP/cIAP1 antagonist
Birinapant, also known as TL32711, is a synthetic small molecule and peptido mimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins, with potential antineoplastic activity.
Grouped product items
Product Name Price Stock Qty
Birinapant (TL32711) 5mg
$70.00
In stock
Birinapant (TL32711) 10mg
$120.00
In stock
Birinapant (TL32711) 25mg
$200.00
In stock
Birinapant (TL32711) 50mg
$280.00
In stock
Birinapant (TL32711) 10mM * 1mL in DMSO
$100.00
In stock
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Biological Activity
Discription Birinapant, also known as TL32711, is a synthetic small molecule and peptido mimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins, with potential antineoplastic activity.
Targets
Target Value
Product Information
Catalog Num A12738
Formula C42H56F2N8O6
Molecular Weight 806.94
CAS Number 1260251-31-7
SMILES CC[C@@H](C(=O)N1C[C@H](C[C@H]1CC2=C(NC3=C2C=CC(=C3)F)C4=C(C5=C(N4)C=C(C=C5)F)C[C@@H]6C[C@@H](CN6C(=O)[C@H](CC)NC(=O)[C@H](C)NC)O)O)NC(=O)[C@H](C)NC
Synonyms TL-32711, TL 32711
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 87 mg/mL (107.81 mM)
Water Insoluble
Ethanol 48 mg/mL (59.48 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 12.39 mL 61.96 mL 123.92 mL
0.5 mM 2.48 mL 12.39 mL 24.78 mL
1 mM 1.24 mL 6.2 mL 12.39 mL
5 mM 0.25 mL 1.24 mL 2.48 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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