Birinapant (TL32711)

Catalog No.: A12738
XIAP/cIAP1 antagonist
Birinapant, also known as TL32711, is a synthetic small molecule and peptido mimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins, with potential antineoplastic activity.
Grouped product items
Product Name Price Stock Qty
Birinapant (TL32711) 5mg
Special Price $56.00 Regular Price $70.00
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Birinapant (TL32711) 10mg
Special Price $96.00 Regular Price $120.00
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Birinapant (TL32711) 25mg
Special Price $160.00 Regular Price $200.00
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Birinapant (TL32711) 50mg
Special Price $224.00 Regular Price $280.00
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Birinapant (TL32711) 10mM * 1mL in DMSO
Special Price $80.00 Regular Price $100.00
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Adooq Products cited in reputable paper
Adooq's Birinapant (TL32711) has been cited by 1 publications
  • Antonella Antignani, .et al. , FASEB J, 2023, Dec;37(12):e23292 PMID: 37971407
  • Biological Activity
    Discription Birinapant, also known as TL32711, is a synthetic small molecule and peptido mimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins, with potential antineoplastic activity.
    Targets
    Target Value
    Product Information
    Catalog Num A12738
    Formula C42H56F2N8O6
    Molecular Weight 806.94
    CAS Number 1260251-31-7
    SMILES CC[C@@H](C(=O)N1C[C@H](C[C@H]1CC2=C(NC3=C2C=CC(=C3)F)C4=C(C5=C(N4)C=C(C=C5)F)C[C@@H]6C[C@@H](CN6C(=O)[C@H](CC)NC(=O)[C@H](C)NC)O)O)NC(=O)[C@H](C)NC
    Synonyms TL-32711, TL 32711
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 87 mg/mL (107.81 mM)
    Water Insoluble
    Ethanol 48 mg/mL (59.48 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 12.39 mL 61.96 mL 123.92 mL
    0.5 mM 2.48 mL 12.39 mL 24.78 mL
    1 mM 1.24 mL 6.2 mL 12.39 mL
    5 mM 0.25 mL 1.24 mL 2.48 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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