Bis-PEG4-NHS ester serves as an amine-reactive crosslinking reagent that targets primary amine groups on liposome surfaces, facilitating the formation of covalent amide bonds. The hydrophilic PEG4 spacer minimizes steric hindrance, allowing for efficient site-specific antibody coupling via copper-free strain-promoted azide-alkyne cycloaddition without compromising liposome integrity. Additionally, Bis-PEG4-NHS ester hydrolyzes during annealing to generate -COOH groups, which enhance perovskite structural integrity, passivate defects, and refine nucleation kinetics, ultimately improving crystal growth. This compound is also beneficial as an antisolvent additive in p−i−n perovskite solar cells, contributing to enhanced device efficiency and long-term stability.
Bis-PEG4-NHS ester serves as an amine-reactive crosslinking reagent that targets primary amine groups on liposome surfaces, facilitating the formation of covalent amide bonds. The hydrophilic PEG4 spacer minimizes steric hindrance, allowing for efficient site-specific antibody coupling via copper-free strain-promoted azide-alkyne cycloaddition without compromising liposome integrity. Additionally, Bis-PEG4-NHS ester hydrolyzes during annealing to generate -COOH groups, which enhance perovskite structural integrity, passivate defects, and refine nucleation kinetics, ultimately improving crystal growth. This compound is also beneficial as an antisolvent additive in p−i−n perovskite solar cells, contributing to enhanced device efficiency and long-term stability.
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