BMS-159

Catalog No.: A36927
Phosphate Prodrug of BMS-135
BMS-159 is an orally bioavailable phosphate prodrug of BMS-135, functioning as a potent ATP-competitive inhibitor of casein kinase 2 (CK2). This compound exhibits significant biological activity in inhibiting CK2, which is implicated in various cellular processes. BMS-159 is utilized in research focusing on neurological disorders and tumor biology, providing valuable insights into therapeutic strategies targeting CK2-related pathways.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBMS-159 is an orally bioavailable phosphate prodrug of BMS-135, functioning as a potent ATP-competitive inhibitor of casein kinase 2 (CK2). This compound exhibits significant biological activity in inhibiting CK2, which is implicated in various cellular processes. BMS-159 is utilized in research focusing on neurological disorders and tumor biology, providing valuable insights into therapeutic strategies targeting CK2-related pathways.
Product Information
Catalog NumA36927
FormulaC22H24ClN10O6P
Molecular Weight590.92
CAS Number1541248-45-6
SMILESN#CC1=CN=C2N1N=C(N=C2NCC)NC3=C(C(N4C[C@H]([C@@H](CC4)NC(OC)=O)OP(O)(O)=O)=CC(C#N)=C3)Cl
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