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BMS-185354

Catalog No.: A77497
RARγ Activator
BMS-185354 is a selective retinoic acid receptor gamma (RARγ) activator, exhibiting an EC50 value of 28 nM. This compound plays a significant role in modulating gene expression involved in various biological processes. BMS-185354 is primarily utilized in cancer research to investigate the therapeutic potential of targeting RARγ pathways in oncogenesis and tumor progression.
BMS-185354 110952-22-2 RARγ Activator
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBMS-185354 is a selective retinoic acid receptor gamma (RARγ) activator, exhibiting an EC50 value of 28 nM. This compound plays a significant role in modulating gene expression involved in various biological processes. BMS-185354 is primarily utilized in cancer research to investigate the therapeutic potential of targeting RARγ pathways in oncogenesis and tumor progression.
Product Information
Catalog NumA77497
FormulaC26H27NO3
Molecular Weight401.50
CAS Number110952-22-2
SMILESO=C(C1=CC2=CC=C(/C(C3=CC=C4C(C(C)(CCC4(C)C)C)=C3)=N/O)C=C2C=C1)O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

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Metabolism > Retinoid Receptor