BMS-229724 is a potent, orally active inhibitor of cytosolic phospholipase A2 (cPLA2), exhibiting an IC50 of 2.8 μM. This compound effectively inhibits the production of arachidonic acid and eicosanoids in various cell types, including U937 cells, neutrophils, and platelets. With demonstrated anti-inflammatory properties, BMS-229724 is valuable for research into skin inflammation and related inflammatory diseases.
BMS-229724 is a potent, orally active inhibitor of cytosolic phospholipase A2 (cPLA2), exhibiting an IC50 of 2.8 μM. This compound effectively inhibits the production of arachidonic acid and eicosanoids in various cell types, including U937 cells, neutrophils, and platelets. With demonstrated anti-inflammatory properties, BMS-229724 is valuable for research into skin inflammation and related inflammatory diseases.
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