BMS-341400 mesylate

Catalog No.: A42253
PDE5 Inhibitor
BMS-341400 mesylate is a selective phosphodiesterase 5 (PDE5) inhibitor, exhibiting an IC50 value of 0.3 nM. This compound attenuates the degradation of cyclic guanosine monophosphate (cGMP), thereby facilitating nitric oxide (NO)-induced relaxation of corpus cavernosum smooth muscle and enhancing erectile function. BMS-341400 mesylate serves as a valuable tool for investigating mechanisms underlying erectile dysfunction.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Biological Activity
DescriptionBMS-341400 mesylate is a selective phosphodiesterase 5 (PDE5) inhibitor, exhibiting an IC50 value of 0.3 nM. This compound attenuates the degradation of cyclic guanosine monophosphate (cGMP), thereby facilitating nitric oxide (NO)-induced relaxation of corpus cavernosum smooth muscle and enhancing erectile function. BMS-341400 mesylate serves as a valuable tool for investigating mechanisms underlying erectile dysfunction.
Product Information
Catalog NumA42253
FormulaC24H26ClN9O5S
Molecular Weight588.04
CAS Number296250-54-9
SMILESCCN1C2=C(C3=C(C(N4C=C(C(NC)=O)N=C4)=NN=C3NCC5=CC(Cl)=C(OC)C=C5)C=N2)C=N1.CS(O)(=O)=O
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