BMS-687453

Catalog No.: A15836
PPAR agonist
BMS-687453 is a potent and selective peroxisome proliferator activated receptor (PPAR) alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgamma in PPAR-GAL4 transactivation assays.
Grouped product items
Product Name Price Stock Qty
BMS-687453 5mg
$110.00
In stock
BMS-687453 10mg
$180.00
In stock
BMS-687453 25mg
$360.00
In stock
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Biological Activity
Discription BMS-687453 is a potent and selective peroxisome proliferator activated receptor (PPAR) alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgamma in PPAR-GAL4 transactivation assays.
Targets
Target Value
Product Information
Catalog Num A15836
Formula C22H21ClN2O6
Molecular Weight 444.86
CAS Number 1000998-59-3
SMILES O=C(O)CN(CC1=CC=CC(OCC2=C(C)OC(C3=CC=C(Cl)C=C3)=N2)=C1)C(OC)=O
Synonyms BMS687453, BMS 687453
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 80 mg/mL (179.83 mM)
Water Insoluble
Ethanol 80 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.48 mL 112.39 mL 224.79 mL
0.5 mM 4.5 mL 22.48 mL 44.96 mL
1 mM 2.25 mL 11.24 mL 22.48 mL
5 mM 0.45 mL 2.25 mL 4.5 mL
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