BMS-795311 is a potent cholesteryl ester transfer protein (CETP) inhibitor, demonstrating an IC50 of 4 nM in enzyme-based scintillation proximity assays and 0.22 μM in human whole plasma assays. This compound is utilized in research to explore lipid metabolism and its implications in cardiovascular diseases. Its oral bioavailability supports in vivo studies, making it a valuable tool in understanding CETP's role in lipid transport and potential therapeutic strategies for dyslipidemia.
BMS-795311 is a potent cholesteryl ester transfer protein (CETP) inhibitor, demonstrating an IC50 of 4 nM in enzyme-based scintillation proximity assays and 0.22 μM in human whole plasma assays. This compound is utilized in research to explore lipid metabolism and its implications in cardiovascular diseases. Its oral bioavailability supports in vivo studies, making it a valuable tool in understanding CETP's role in lipid transport and potential therapeutic strategies for dyslipidemia.
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