Biological Activity
BMS-986205, also known as Linrodostat, ONO-7701 and F001287, a potent and selective, orally active IDO1 inhibitor with potential immunomodulating and antineoplastic activities. CAS: 1923833-60-6 (free base) 2221034-29-1 (mesylate)
In vitro | DMSO | 74 mg/mL (180.08 mM) | |
Water | Insoluble | ||
Ethanol | 74 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.34 mL | 121.68 mL | 243.36 mL |
0.5 mM | 4.87 mL | 24.34 mL | 48.67 mL |
1 mM | 2.43 mL | 12.17 mL | 24.34 mL |
5 mM | 0.49 mL | 2.43 mL | 4.87 mL |
*The above data is based on the productmolecular weight 410.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A17013 |
---|---|
Actions | Inhibitor |
CAS No. | 1923833-60-6 |
Formula | C24H24ClFN2O |
M. Wt | 410.91 |
Purity | >98% |
Synonyms | BMS 986205, BMS986205, ONO-7701; ONO 7701, ONO7701, F-001287, F001287, F001287, Linrodostat |
SMILES | C[[email protected]]([[email protected]]1CC[[email protected]@H](C2=CC=NC3=CC=C(F)C=C23)CC1)C(NC4=CC=C(Cl)C=C4)=O |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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