BMS-986482 is a CRBN-mediated IKZF degrader that selectively targets the IKZF1-4 protein family. Its unique CELMoD™ core facilitates the degradation of these proteins, leading to impaired tumor growth as demonstrated in preclinical mouse models. This compound is particularly valuable for research focused on advanced solid tumors, providing insights into therapeutic strategies that disrupt IKZF protein function.
BMS-986482 is a CRBN-mediated IKZF degrader that selectively targets the IKZF1-4 protein family. Its unique CELMoD™ core facilitates the degradation of these proteins, leading to impaired tumor growth as demonstrated in preclinical mouse models. This compound is particularly valuable for research focused on advanced solid tumors, providing insights into therapeutic strategies that disrupt IKZF protein function.
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