BMS711939 is a selective agonist of peroxisome proliferator-activated receptor α (PPAR α), demonstrating an EC50 of 4 nM for human PPARα and 4.5 μM for human PPARγ. This compound shows promising pharmacokinetic properties in rat models and is known to elevate HDL cholesterol levels while decreasing LDL cholesterol and triglycerides. BMS711939 serves as a valuable tool for investigating lipid metabolism and the physiological effects of PPAR activation.
BMS711939 is a selective agonist of peroxisome proliferator-activated receptor α (PPAR α), demonstrating an EC50 of 4 nM for human PPARα and 4.5 μM for human PPARγ. This compound shows promising pharmacokinetic properties in rat models and is known to elevate HDL cholesterol levels while decreasing LDL cholesterol and triglycerides. BMS711939 serves as a valuable tool for investigating lipid metabolism and the physiological effects of PPAR activation.
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