Boc-Gln-Gly-Arg-AMC

Catalog No.: A77696
Fluorogenic Substrate
Boc-Gln-Gly-Arg-AMC is a fluorogenic substrate specifically designed for the serine proteases factor XIIa and trypsin. Upon cleavage of the amide bond between arginine and the methylcoumarin amide moiety, it releases the fluorescent compound 7-Amino-4-methylcoumarin, enabling sensitive detection. This substrate is instrumental in studying proteolytic activity and can be utilized in various biochemical assays to monitor enzyme function.
Grouped product items
Size Price Stock Qty
1mg
$95.00
In stock
5mg
$245.00
In stock
10mg
$420.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBoc-Gln-Gly-Arg-AMC is a fluorogenic substrate specifically designed for the serine proteases factor XIIa and trypsin. Upon cleavage of the amide bond between arginine and the methylcoumarin amide moiety, it releases the fluorescent compound 7-Amino-4-methylcoumarin, enabling sensitive detection. This substrate is instrumental in studying proteolytic activity and can be utilized in various biochemical assays to monitor enzyme function.
Product Information
Catalog NumA77696
FormulaC28H40N8O8
Molecular Weight616.67
CAS Number113865-85-3
Sequence{Boc-Gln}-Gly-{Arg-AMC}
Sequence shortening{Boc-Gln}-G-{Arg-AMC}
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