Bodilisant

Catalog No.: A34016
Histamine Receptor
Bodilisant is a fluorescent ligand for the histamine H3 receptor (hH3R). It demonstrates high affinity, allowing detection of hH3R activity in cells overexpressing the receptor at low concentrations (1-10 nM) and in hH3R-rich tissues at approximately 1 μM. This compound serves as a valuable pharmacological tool for receptor imaging and offers insights into histamine receptor signaling pathways in research applications.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBodilisant is a fluorescent ligand for the histamine H3 receptor (hH3R). It demonstrates high affinity, allowing detection of hH3R activity in cells overexpressing the receptor at low concentrations (1-10 nM) and in hH3R-rich tissues at approximately 1 μM. This compound serves as a valuable pharmacological tool for receptor imaging and offers insights into histamine receptor signaling pathways in research applications.
Product Information
Catalog NumA34016
FormulaC27H34BF2N3O
Molecular Weight465.39
CAS Number1416130-06-7
SMILES[F-][B+3]1([N]2=C(C)C=C(C)C2=C(C3=C(C)C=C(C)[N-]31)C4=CC=C(C=C4)OCCCN5CCCCC5)[F-]
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