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BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2.
Targets
| Endothelin A receptor | ||||
| 7.3 nM |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.37 mL | 81.87 mL | 163.75 mL |
| 0.5 mM | 3.27 mL | 16.37 mL | 32.75 mL |
| 1 mM | 1.64 mL | 8.19 mL | 16.37 mL |
| 5 mM | 0.33 mL | 1.64 mL | 3.27 mL |
*The above data is based on the productmolecular weight 610.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Chemical Properties
| Catalog Num | A15912 |
|---|---|
| Actions | Antagonist |
| M. Wt | 610.7 |
| Formula | C31H42N6O7 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 136553-81-6 |
| Synonyms | BQ123, BQ 123 |
| SMILES | O=C(O)C[[email protected]]1NC([[email protected]@H](CC2=CNC3=C2C=CC=C3)NC([[email protected]](CC(C)C)NC([[email protected]@H](C(C)C)NC([[email protected]@](CCC4)([H])N4C1=O)=O)=O)=O)=O |
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