BQ0413 is a potent PSMA tracer with a dissociation constant (KD) of 89 pM, demonstrating strong affinity for the prostate-specific membrane antigen. This compound exhibits efficient cellular uptake and a notable internalization rate of 44% in PC3-pip cells, making it suitable for research applications in tumor imaging. When radiolabeled with 99mTc, BQ0413 serves as an effective imaging agent for prostate cancer in preclinical studies.
BQ0413 is a potent PSMA tracer with a dissociation constant (KD) of 89 pM, demonstrating strong affinity for the prostate-specific membrane antigen. This compound exhibits efficient cellular uptake and a notable internalization rate of 44% in PC3-pip cells, making it suitable for research applications in tumor imaging. When radiolabeled with 99mTc, BQ0413 serves as an effective imaging agent for prostate cancer in preclinical studies.
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