BRL-52656 is a potent Kappa opioid receptor (KOR) agonist with the ability to cross the blood-brain barrier. This compound exhibits a biphasic impact on blood pressure, reducing it at lower doses while causing an increase at higher doses in spontaneously hypertensive rats. Furthermore, BRL-52656 induces water diuresis by inhibiting vasopressin (AVP) secretion, making it relevant for research in cardiovascular and renal physiology.
BRL-52656 is a potent Kappa opioid receptor (KOR) agonist with the ability to cross the blood-brain barrier. This compound exhibits a biphasic impact on blood pressure, reducing it at lower doses while causing an increase at higher doses in spontaneously hypertensive rats. Furthermore, BRL-52656 induces water diuresis by inhibiting vasopressin (AVP) secretion, making it relevant for research in cardiovascular and renal physiology.
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