Bromoenol lactone is a selective and potent irreversible inhibitor of calcium-independent phospholipase A2 (iPLA2β), exhibiting an IC50 of approximately 7 μM. This compound effectively inhibits antigen-stimulated mast cell exocytosis without interfering with calcium influx. Bromoenol lactone is valuable for research applications aimed at understanding the roles of phospholipases in cellular processes and inflammatory responses.
Bromoenol lactone is a selective and potent irreversible inhibitor of calcium-independent phospholipase A2 (iPLA2β), exhibiting an IC50 of approximately 7 μM. This compound effectively inhibits antigen-stimulated mast cell exocytosis without interfering with calcium influx. Bromoenol lactone is valuable for research applications aimed at understanding the roles of phospholipases in cellular processes and inflammatory responses.
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