Bufrolin

Catalog No.: A33889
GPR35 Agonist
Bufrolin is a potent agonist of GPR35, known for its ability to promote the interaction between β-arrestin-2 and both human GPR35a and rat GPR35. This compound exhibits significant antiallergic properties by stabilizing mast cells and inhibiting inflammatory responses associated with internalization peptides. Bufrolin is valuable for research into anti-inflammatory mechanisms and therapeutic applications targeting GPR35-related pathways.
Grouped product items
Size Price Stock Qty
1mg
$560.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
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Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBufrolin is a potent agonist of GPR35, known for its ability to promote the interaction between β-arrestin-2 and both human GPR35a and rat GPR35. This compound exhibits significant antiallergic properties by stabilizing mast cells and inhibiting inflammatory responses associated with internalization peptides. Bufrolin is valuable for research into anti-inflammatory mechanisms and therapeutic applications targeting GPR35-related pathways.
Product Information
Catalog NumA33889
FormulaC18H16N2O6
Molecular Weight356.33
CAS Number54867-56-0
SMILESO=C1C2=C3C(C(C=C(C(O)=O)N3)=O)=CC(CCCC)=C2NC(C(O)=O)=C1
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