c-RGD-SH is a selective ligand for integrin αvβ3, playing a crucial role in tumor cell adhesion and migration. When conjugated with core-crosslinked polymeric micelles (CCPM), it can be utilized to synthesize a dual modality nanoparticle probe. This probe, labeled with Cy7 and 111In, facilitates both SPECT and near-infrared fluorescence (NIRF) imaging in tumor research applications, enabling enhanced visualization and targeting of cancerous tissues.
c-RGD-SH is a selective ligand for integrin αvβ3, playing a crucial role in tumor cell adhesion and migration. When conjugated with core-crosslinked polymeric micelles (CCPM), it can be utilized to synthesize a dual modality nanoparticle probe. This probe, labeled with Cy7 and 111In, facilitates both SPECT and near-infrared fluorescence (NIRF) imaging in tumor research applications, enabling enhanced visualization and targeting of cancerous tissues.
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