C188-9 is a potent inhibitor of STAT3 that binds to STAT3 with high affinity (KD=4.7??0.4 nM). C188-9 is well tolerated in mice, shows good oral bioavailability, and is concentrated in tumors.
C188-9 is a potent inhibitor of STAT3 that binds to STAT3 with high affinity (KD=4.7??0.4 nM). C188-9 is well tolerated in mice, shows good oral bioavailability, and is concentrated in tumors.
C 188-9; C-188-9; C-1889; C1889; C 1889; C-1889; F0808-0084;
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro
DMSO
81 mg/mL (171.78 mM)
Water
Insoluble
Ethanol
5 mg/mL (10.6 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula: