C25-140

Catalog No.: A18705
TRAF6-Ubc13 inhibitor
C25-140, a first-in-class, fairly selective TRAF6-Ubc13 inhibitor, directly binds to TRAF6, and blocks the interaction of TRAF6 with Ubc13. C25-140 lowers TRAF6 activity, reduces NF-κB activation, and combats autoimmunity.
Grouped product items
Product Name Price Stock Qty
C25-140 5mg
Special Price $128.00 Regular Price $160.00
In stock
C25-140 10mg
Special Price $208.00 Regular Price $260.00
In stock
C25-140 50mg
Special Price $704.00 Regular Price $880.00
In stock
C25-140 100mg
Special Price $1,264.00 Regular Price $1,580.00
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Biological Activity
Discription C25-140, a first-in-class, fairly selective TRAF6-Ubc13 inhibitor, directly binds to TRAF6, and blocks the interaction of TRAF6 with Ubc13. C25-140 lowers TRAF6 activity, reduces NF-κB activation, and combats autoimmunity.
Product Information
Catalog Num A18705
Formula C26H31N7O
Molecular Weight 457.57
CAS Number 1358099-18-9
SMILES O=C(N1CCC(CC2=CC=CC=C2)CC1)CCC3=C(C)N(C4=NN5C(C=C4)=NN=C5C)N=C3C
Synonyms C25140; C-25140; C 25140; C25 140; C25-140; C-25-140;
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 89 mg/mL (194.5 mM)
Water Insoluble
Ethanol 89 mg/mL (194.5 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.85 mL 109.27 mL 218.55 mL
0.5 mM 4.37 mL 21.85 mL 43.71 mL
1 mM 2.19 mL 10.93 mL 21.85 mL
5 mM 0.44 mL 2.19 mL 4.37 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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