C25-140

Catalog No.: A18705

TRAF6-Ubc13 inhibitor

C25-140

C25-140 Chemical Structure

CAS NO. 1358099-18-9

C25-140, a first-in-class, fairly selective TRAF6-Ubc13 inhibitor, directly binds to TRAF6, and blocks the interaction of TRAF6 with Ubc13. C25-140 lowers TRAF6 activity, reduces NF-κB activation, and combats autoimmunity.

Availability: In stock

Package Price Qty
5 mg
$160.00
10 mg
$260.00
50 mg
$880.00
100 mg
$1,580.00
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Biological Activity

C25-140, a first-in-class, fairly selective TRAF6-Ubc13 inhibitor, directly binds to TRAF6, and blocks the interaction of TRAF6 with Ubc13. C25-140 lowers TRAF6 activity, reduces NF-κB activation, and combats autoimmunity.
In vitro DMSO 89 mg/mL (194.5 mM)
Water Insoluble
Ethanol 89 mg/mL (194.5 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.85 mL 109.27 mL 218.55 mL
0.5 mM 4.37 mL 21.85 mL 43.71 mL
1 mM 2.19 mL 10.93 mL 21.85 mL
5 mM 0.44 mL 2.19 mL 4.37 mL

*The above data is based on the productmolecular weight 457.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18705
Actions Inhibitor
CAS No. 1358099-18-9
Formula C26H31N7O
M. Wt 457.57
Solubility DMSO
Purity >98%
Synonyms C25140; C-25140; C 25140; C25 140; C25-140; C-25-140;
SMILES O=C(N1CCC(CC2=CC=CC=C2)CC1)CCC3=C(C)N(C4=NN5C(C=C4)=NN=C5C)N=C3C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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