C25-140

Catalog No.: A18705

TRAF6-Ubc13 inhibitor

C25-140

C25-140 Chemical Structure

CAS NO. 1358099-18-9

C25-140, a first-in-class, fairly selective TRAF6-Ubc13 inhibitor, directly binds to TRAF6, and blocks the interaction of TRAF6 with Ubc13. C25-140 lowers TRAF6 activity, reduces NF-κB activation, and combats autoimmunity.

Availability: In stock

Package Price Qty
5 mg
$160.00
10 mg
$260.00
50 mg
$880.00
100 mg
$1,580.00
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Biological Activity

C25-140, a first-in-class, fairly selective TRAF6-Ubc13 inhibitor, directly binds to TRAF6, and blocks the interaction of TRAF6 with Ubc13. C25-140 lowers TRAF6 activity, reduces NF-κB activation, and combats autoimmunity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.85 mL 109.27 mL 218.55 mL
0.5 mM 4.37 mL 21.85 mL 43.71 mL
1 mM 2.19 mL 10.93 mL 21.85 mL
5 mM 0.44 mL 2.19 mL 4.37 mL

*The above data is based on the productmolecular weight 457.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18705
Actions Inhibitor
M. Wt 457.57
Formula C26H31N7O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1358099-18-9
Synonyms C25140; C-25140; C 25140; C25 140; C25-140; C-25-140;
SMILES O=C(N1CCC(CC2=CC=CC=C2)CC1)CCC3=C(C)N(C4=NN5C(C=C4)=NN=C5C)N=C3C

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