C3001a is a selective activator of the TREK-1 and TREK-2 potassium channels, exhibiting EC50 values of 12.81 μM and 11.31 μM, respectively. This compound specifically interacts with the cryptic binding site formed by P1 and TM4 in TREK-1, with no impact on other two-pore domain K+ channels. C3001a is applicable in research exploring pain mechanisms and pancreatitis.
C3001a is a selective activator of the TREK-1 and TREK-2 potassium channels, exhibiting EC50 values of 12.81 μM and 11.31 μM, respectively. This compound specifically interacts with the cryptic binding site formed by P1 and TM4 in TREK-1, with no impact on other two-pore domain K+ channels. C3001a is applicable in research exploring pain mechanisms and pancreatitis.
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