CADD522

Catalog No.: A19399

RUNX2-DNA binding inhibitor

CADD522

CADD522 Chemical Structure

CAS NO. 199735-88-1

CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM. CADD522 exhibits antitumor activity.

Availability: In stock

Package Price Qty
5 mg
$60.00
10 mg
$100.00
50 mg
$350.00
100 mg
$600.00
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Biological Activity

CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM. CADD522 exhibits antitumor activity.
In vitro DMSO 58 mg/mL (177.82 mM)
Water Insoluble
Ethanol 58 mg/mL (177.82 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.66 mL 153.29 mL 306.59 mL
0.5 mM 6.13 mL 30.66 mL 61.32 mL
1 mM 3.07 mL 15.33 mL 30.66 mL
5 mM 0.61 mL 3.07 mL 6.13 mL

*The above data is based on the productmolecular weight 326.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A19399
Actions Inhibitor
CAS No. 199735-88-1
Formula C15H13Cl2NO3
M. Wt 326.17
Purity >98%
Synonyms CADD 522, CADD-522
SMILES ClC1=C(Cl)C=CC(NC(C2C(C3)C=CC3C2C(O)=O)=O)=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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