Calcifediol

Catalog No.: A11367

Calcifediol

Calcifediol Chemical Structure

CAS NO. 19356-17-3

Calcifediol is a major circulating metabolite of vitamin D3 and acts as a competitive inhibitor with an apparent Ki of 3.9 μM. It also suppresses PTH secretion and mRNA (ED50=2 nM)

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5 mg

Regular Price: $110.00

Special Price $88.00

10 mg

Regular Price: $200.00

Special Price $160.00

25 mg

Regular Price: $450.00

Special Price $360.00

50 mg

Regular Price: $750.00

Special Price $600.00

10mM * 1mL in DMSO

Regular Price: $147.00

Special Price $117.60

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Biological Activity

Calcifediol is a major circulating metabolite of vitamin D3 and acts as a competitive inhibitor with an apparent Ki of 3.9 μM. It also suppresses PTH secretion and mRNA (ED50=2 nM)
In vitro (25°C) DMSO 74 mg/mL (184.7 mM)
Water Insoluble
Ethanol 18 mg/mL (44.93 mM)
In vivo 2% DMSO+30% PEG 300+5% Tween+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.96 mL 124.8 mL 249.6 mL
0.5 mM 4.99 mL 24.96 mL 49.92 mL
1 mM 2.5 mL 12.48 mL 24.96 mL
5 mM 0.5 mL 2.5 mL 4.99 mL

*The above data is based on the productmolecular weight 400.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11367
CAS No. 19356-17-3
Formula C27H44O2
M. Wt 400.64
Purity >98%
Synonyms 25-Hydroxyvitamin D3, Calcidiol
SMILES C[[email protected]](CCCC(C)(C)O)[[email protected]]1CC[[email protected]@H]\2[[email protected]@]1(CCC/C2=C\C=C/3\C[[email protected]](CCC3=C)O)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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