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Biological Activity
Rp-cAMPS is a cell-permeable and reversible inhibitor of PKA (protein kinase A) (Ki = 11 uM). Rp-cAMPS is resistant to hydrolysis by phosphodiesterases and is noncompetitive with respect to ATP.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.4 mL | 111.99 mL | 223.98 mL |
| 0.5 mM | 4.48 mL | 22.4 mL | 44.8 mL |
| 1 mM | 2.24 mL | 11.2 mL | 22.4 mL |
| 5 mM | 0.45 mL | 2.24 mL | 4.48 mL |
*The above data is based on the productmolecular weight 446.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16028 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 151837-09-1 |
| Formula | C10H12N5O5PS.C6H15N |
| M. Wt | 446.46 |
| Purity | >98% |
| Synonyms | Rp-cAMPS |
| SMILES | CCN(CC)CC.C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C3N=CN=C4N)O)OP(=S)(O1)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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