Cangrelor Tetrasodium

Catalog No.: A17919
P2Y12 receptors inhibitor
Cangrelor Tetrasodium is a high-affinity, reversible inhibitor of P2Y12 receptors that causes almost complete inhibition of ADP-induced platelet aggregate. It is a modified ATP derivative stable to enzymatic degradation. Unlike clopidogrel (Plavix), which is a prodrug, cangrelor is an active drug not requiring metabolic conversion.
Grouped product items
Size Price Stock Qty
1mg
$30.00
In stock
2mg
$50.00
In stock
5mg
$85.00
In stock
10mg
$135.00
In stock
25mg
$255.00
In stock
50mg
$450.00
In stock
100mg
$650.00
In stock
500mg
$1,355.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Other Forms of Cangrelor Tetrasodium

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCangrelor Tetrasodium is a high-affinity, reversible inhibitor of P2Y12 receptors that causes almost complete inhibition of ADP-induced platelet aggregate. It is a modified ATP derivative stable to enzymatic degradation. Unlike clopidogrel (Plavix), which is a prodrug, cangrelor is an active drug not requiring metabolic conversion.
Targets
TargetValue
Product Information
Catalog NumA17919
FormulaC17H21Cl2F3N5Na4O12P3S2
Molecular Weight864.27
CAS Number163706-36-3
SMILESCSCCNC1=NC(SCCC(F)(F)F)=NC2=C1N=CN2[C@@H]3O[C@H](COP([O-])(OP([O-])(C(P([O-])([O-])=O)(Cl)Cl)=O)=O)[C@@H](O)[C@H]3O.[Na+].[Na+].[Na+].[Na+]
SynonymsCangrelor Tetrasodium; AR-C69931MX; AR C69931MX; ARC69931MX
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO2 mg/mL (2.31 mM)
Water87 mg/mL (100.66 mM)
EthanolInsoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM11.57 mL57.85 mL115.7 mL
0.5 mM2.31 mL11.57 mL23.14 mL
1 mM1.16 mL5.79 mL11.57 mL
5 mM0.23 mL1.16 mL2.31 mL
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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