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Capsid assembly inhibitor

Catalog No.: A51677
12-mer Peptide
Capsid assembly inhibitor is a 12-mer peptide that specifically targets the capsid (CA) domain of the Gag protein, effectively inhibiting the assembly of both immature and mature HIV-1 capsid particles in vitro. This compound serves as a valuable tool for studying HIV-1 replication mechanisms and evaluating potential antiviral strategies. Its ability to interfere with capsid formation makes it ideal for research in virology and the development of therapeutic agents against HIV-1.
Capsid assembly inhibitor 865292-94-0 12-mer Peptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCapsid assembly inhibitor is a 12-mer peptide that specifically targets the capsid (CA) domain of the Gag protein, effectively inhibiting the assembly of both immature and mature HIV-1 capsid particles in vitro. This compound serves as a valuable tool for studying HIV-1 replication mechanisms and evaluating potential antiviral strategies. Its ability to interfere with capsid formation makes it ideal for research in virology and the development of therapeutic agents against HIV-1.
Product Information
Catalog NumA51677
FormulaC69H96N12O22
Molecular Weight1445.57
CAS Number865292-94-0
SequenceIle-Thr-Phe-Glu-Asp-Leu-Leu-Asp-Tyr-Tyr-Gly-Pro
Sequence shorteningITFEDLLDYYGP
SMILES[C@H](CC1=CC=C(O)C=C1)(C(N[C@@H](CC2=CC=C(O)C=C2)C(NCC(=O)N3[C@H](C(O)=O)CCC3)=O)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC4=CC=CC=C4)NC([C@@H](NC([C@H]([C@H](CC)C)N)=O)[C@@H](C)O)=O)=O)CCC(O)=O)=O)CC(O)=O)=O)CC(C)C)=O)CC(C)C)=O)CC(O)=O)=O
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