Biological Activity
Captopril Disulfide is a reversible and competitive inhibitor of LTA4 hydrolase (IC50=11 M). Captopril has been shown to be an of angiotensin converting enzyme-1 (ACE1), but not ACE2(IC50 = 22 nM).
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 23.12 mL | 115.59 mL | 231.19 mL |
0.5 mM | 4.62 mL | 23.12 mL | 46.24 mL |
1 mM | 2.31 mL | 11.56 mL | 23.12 mL |
5 mM | 0.46 mL | 2.31 mL | 4.62 mL |
*The above data is based on the productmolecular weight 432.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A13521 |
---|---|
Actions | Inhibitor |
M. Wt | 432.55 |
Formula | C18H28N2O6S2 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 64806-05-9 |
Synonyms | SQ 14,551 |
SMILES | C[[email protected]](CSSCC(C)C(=O)N1CCC[[email protected]]1C(=O)O)C(=O)N2CCC[[email protected]]2C(=O)O |
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