Casein kinase 1δ-IN-27 is a selective inhibitor of casein kinase 1, effectively targeting CK1α, CK1δ, CK1ε, and p38α with IC50 values of 22 nM, 16.5 nM, 9.41 nM, and 14.8 nM, respectively. Notably, it demonstrates significant activity in inhibiting DUX4 expression with an IC50 of 10 nM. This reagent is valuable for research applications focused on CK1-related signaling pathways and their implications in various biological processes.
Casein kinase 1δ-IN-27 is a selective inhibitor of casein kinase 1, effectively targeting CK1α, CK1δ, CK1ε, and p38α with IC50 values of 22 nM, 16.5 nM, 9.41 nM, and 14.8 nM, respectively. Notably, it demonstrates significant activity in inhibiting DUX4 expression with an IC50 of 10 nM. This reagent is valuable for research applications focused on CK1-related signaling pathways and their implications in various biological processes.
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