Catramilast

Catalog No.: A42168
PDE4D Inhibitor
Catramilast is a selective inhibitor of phosphodiesterase 4D (PDE4D), which plays a crucial role in the regulation of intracellular signaling pathways. This compound is primarily utilized in research focused on pain modulation and inflammatory responses. Its ability to enhance cyclic AMP levels makes it a valuable tool for studying PDE4-mediated biological processes and therapeutic interventions.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCatramilast is a selective inhibitor of phosphodiesterase 4D (PDE4D), which plays a crucial role in the regulation of intracellular signaling pathways. This compound is primarily utilized in research focused on pain modulation and inflammatory responses. Its ability to enhance cyclic AMP levels makes it a valuable tool for studying PDE4-mediated biological processes and therapeutic interventions.
Product Information
Catalog NumA42168
FormulaC17H22N2O3
Molecular Weight302.37
CAS Number183659-72-5
SMILESCOC(C=CC([C@H](C)CN1C(NC=C1)=O)=C2)=C2OCC3CC3
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