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CB-6644 is a selective inhibitor of RUVBL1/2 complex with anti-cancer activity. CB-6644 blocks the ATPase activity of RUVBL1/2 with an IC50 of 15 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.45 mL | 87.25 mL | 174.5 mL |
| 0.5 mM | 3.49 mL | 17.45 mL | 34.9 mL |
| 1 mM | 1.75 mL | 8.73 mL | 17.45 mL |
| 5 mM | 0.35 mL | 1.75 mL | 3.49 mL |
*The above data is based on the productmolecular weight 573.06. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A19157 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 2316817-88-4 |
| Formula | C29H34ClFN4O5 |
| M. Wt | 573.06 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | CB6644, CB 6644 |
| SMILES | COCC1=C(NC(CC(C)(C)CNC(C2=C(OCC)C=C(F)C(Cl)=C2)=O)=O)C(N(N1CCC3)C4=C3C=CC=C4)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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