CB1954

Catalog No.: A15862
CB1954 is a anticancer prodrug that is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent.It can be activated by NAD(P)H quinone oxidoreductase 2.
Grouped product items
Product Name Price Stock Qty
CB1954 10mg
$80.00
In stock
CB1954 25mg
$160.00
In stock
CB1954 50mg
$280.00
In stock
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Biological Activity
Discription CB1954 is a anticancer prodrug that is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent.It can be activated by NAD(P)H quinone oxidoreductase 2.
Product Information
Catalog Num A15862
Formula C9H8N4O5
Molecular Weight 252.18
CAS Number 21919-05-1
SMILES O=C(N)C1=CC(N2CC2)=C([N+]([O-])=O)C=C1[N+]([O-])=O
Synonyms Tretazicar
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 49 mg/mL (194.3 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 39.65 mL 198.27 mL 396.54 mL
0.5 mM 7.93 mL 39.65 mL 79.31 mL
1 mM 3.97 mL 19.83 mL 39.65 mL
5 mM 0.79 mL 3.97 mL 7.93 mL
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