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CB1954 is a anticancer prodrug that is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent.It can be activated by NAD(P)H quinone oxidoreductase 2.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 39.65 mL | 198.27 mL | 396.54 mL |
| 0.5 mM | 7.93 mL | 39.65 mL | 79.31 mL |
| 1 mM | 3.97 mL | 19.83 mL | 39.65 mL |
| 5 mM | 0.79 mL | 3.97 mL | 7.93 mL |
*The above data is based on the productmolecular weight 252.18. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15862 |
|---|---|
| M. Wt | 252.18 |
| Formula | C9H8N4O5 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 21919-05-1 |
| Synonyms | Tretazicar |
| SMILES | O=C(N)C1=CC(N2CC2)=C([N+]([O-])=O)C=C1[N+]([O-])=O |
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