CB1R Allosteric modulator 2

Catalog No.: A59327
CB1R Allosteric Modulator
CB1R Allosteric Modulator 2 is a potent allosteric inhibitor of the cannabinoid receptor type 1 (CB1R). This compound negatively modulates the functional activity of orthosteric ligands at CB1Rs, acting as a negative allosteric modulator (NAM). Its unique mechanism makes it a valuable tool for studying the effects of cannabinoid signaling and its downstream biological pathways, providing insights into potential therapeutic applications in neurological disorders and metabolic regulation.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCB1R Allosteric Modulator 2 is a potent allosteric inhibitor of the cannabinoid receptor type 1 (CB1R). This compound negatively modulates the functional activity of orthosteric ligands at CB1Rs, acting as a negative allosteric modulator (NAM). Its unique mechanism makes it a valuable tool for studying the effects of cannabinoid signaling and its downstream biological pathways, providing insights into potential therapeutic applications in neurological disorders and metabolic regulation.
Product Information
Catalog NumA59327
FormulaC19H15ClFN3O
Molecular Weight355.79
CAS Number2513102-64-0
SMILESO=C(NC1=CC(NC2=CC=C(C=C2)F)=CC=C1)NC3=CC=C(C=C3)Cl
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