CB1R Allosteric Modulator 5 is a selective allosteric modulator targeting the Cannabinoid receptor type 1 (CB1R) with a pIC50 of 6.89. This compound effectively reduces cocaine-seeking behavior associated with cue-induced reinstatement and mitigates cocaine-induced behavioral sensitization, while leaving locomotor activity unaffected. It is suitable for research applications concerning addiction, neuropharmacology, and the modulation of cannabinoid signaling pathways.
CB1R Allosteric Modulator 5 is a selective allosteric modulator targeting the Cannabinoid receptor type 1 (CB1R) with a pIC50 of 6.89. This compound effectively reduces cocaine-seeking behavior associated with cue-induced reinstatement and mitigates cocaine-induced behavioral sensitization, while leaving locomotor activity unaffected. It is suitable for research applications concerning addiction, neuropharmacology, and the modulation of cannabinoid signaling pathways.
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