CB2R antagonist 4

Catalog No.: A59343
CB2R Antagonist
CB2R Antagonist 4 is a selective antagonist and inverse agonist of the cannabinoid receptor type 2 (CB2R) with a pKi of 6.54. This compound exhibits over 11-fold selectivity for CB2R when compared to CB1R, making it a valuable tool for research involving the endocannabinoid system. Its pharmacological properties allow for the exploration of CB2R's role in various neurological processes and disorders.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol 177, Issue 7, p1933-1947.e25
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Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
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Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCB2R Antagonist 4 is a selective antagonist and inverse agonist of the cannabinoid receptor type 2 (CB2R) with a pKi of 6.54. This compound exhibits over 11-fold selectivity for CB2R when compared to CB1R, making it a valuable tool for research involving the endocannabinoid system. Its pharmacological properties allow for the exploration of CB2R's role in various neurological processes and disorders.
Product Information
Catalog NumA59343
FormulaC24H15F3N4O2
Molecular Weight448.40
CAS Number1341021-90-6
SMILESO=C(C1=CC=C2C(N(CC3=CC=C(C=C3)F)C(C4=CC=NN42)=O)=C1)NC5=CC(F)=CC=C5F
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