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CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells, by inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response (UPR) in a subset of MLL-r leukemia cells.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.09 mL | 150.45 mL | 300.91 mL |
| 0.5 mM | 6.02 mL | 30.09 mL | 60.18 mL |
| 1 mM | 3.01 mL | 15.05 mL | 30.09 mL |
| 5 mM | 0.6 mL | 3.01 mL | 6.02 mL |
*The above data is based on the productmolecular weight 332.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18587 |
|---|---|
| M. Wt | 332.33 |
| Formula | C15H12N2O5S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 292053-42-0 |
| Synonyms | CCI006, CCI 006 |
| SMILES | O=C(/C(C#N)=C/C1=CC=C(C2=CC=C(S(=O)(N)=O)C=C2)O1)OC |
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