CCMI

Catalog No.: A21534

α7 nAChR-positive allosteric modulator

CCMI

CCMI Chemical Structure

CAS NO. 917837-54-8

CCMI is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $72.00

Special Price $57.60

10 mg

Regular Price: $124.00

Special Price $99.20

50 mg

Regular Price: $368.00

Special Price $294.40

100 mg

Regular Price: $736.00

Special Price $588.80

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Biological Activity

CCMI is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.76 mL 128.78 mL 257.57 mL
0.5 mM 5.15 mL 25.76 mL 51.51 mL
1 mM 2.58 mL 12.88 mL 25.76 mL
5 mM 0.52 mL 2.58 mL 5.15 mL

*The above data is based on the productmolecular weight 388.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21534
Actions Modulator
CAS No. 917837-54-8
Formula C19H15Cl2N3O2
M. Wt 388.25
Purity >98%
Synonyms IACS10759, IACS 10759
SMILES O=C(NC1=CC=C(Cl)C=C1)/C(C2=CC(C)=NO2)=C/NC3=CC=C(Cl)C=C3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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