CES2A-IN-3 is a potent inhibitor of human carboxylesterase 2A (hCES2A), acting through a serine-targeting covalent mechanism with an IC50 of 0.12 nM. This compound holds significant promise for research applications related to gastrointestinal disorders, including diarrhea and ulcerative colitis, by modulating enzyme activity linked to these conditions. Its high specificity and efficacy make it an essential tool for exploring hCES2A's role in related biological pathways.
CES2A-IN-3 is a potent inhibitor of human carboxylesterase 2A (hCES2A), acting through a serine-targeting covalent mechanism with an IC50 of 0.12 nM. This compound holds significant promise for research applications related to gastrointestinal disorders, including diarrhea and ulcerative colitis, by modulating enzyme activity linked to these conditions. Its high specificity and efficacy make it an essential tool for exploring hCES2A's role in related biological pathways.
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