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Publications citing Adooq Products
CFTRinh-172 Citations (1)
- Dao-Lai Zhang,et al. Gq activity- and 汕-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility, eLife, 2018, 7: e33432 29393851
Chemical Information
| Catalog Num | A12897 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 409.4 |
| Formula | C18H10F3NO3S2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 307510-92-5 |
| Synonyms | CFTR inhibitor 172 |
| SMILES code | C1=CC(=CC(=C1)N2C(=O)/C(=C/C3=CC=C(C=C3)C(=O)O)/SC2=S)C(F)(F)F |
| Chemical Name | Benzoic acid, 4-[[4-oxo-2-thioxo-3-[3-(trifluoromethyl)phenyl]-5-thiazolidinylidene]methyl]- |
Description |
CFTRinh-172 is a voltage-independent, selective CFTR inhibitor | ||||||||||
Targets |
|
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| Solubility (25°C)* | In vitro | DMSO | 82 mg/mL (200.29 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.43 mL | 122.13 mL | 244.26mL |
| 0.5 mM | 4.89 mL | 24.43 mL | 48.85 mL |
| 1 mM | 2.44 mL | 12.21 mL | 24.43 mL |
| 5 mM | 0.49 mL | 2.44 mL | 4.89 mL |
*The above data is based on the productmolecular weight 409.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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