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$0.00 - Dao-Lai Zhang, .et al. Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility, eLife, 2018, 7: e33432 PMID: 29393851
Biological Activity
CFTRinh-172 is a voltage-independent, selective CFTR inhibitor
Targets
| CFTR | ||||
| 300 nM(Ki) |
| In vitro | DMSO | 71 mg/mL (173.42 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.43 mL | 122.13 mL | 244.26 mL |
| 0.5 mM | 4.89 mL | 24.43 mL | 48.85 mL |
| 1 mM | 2.44 mL | 12.21 mL | 24.43 mL |
| 5 mM | 0.49 mL | 2.44 mL | 4.89 mL |
*The above data is based on the productmolecular weight 409.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12897 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 307510-92-5 |
| Formula | C18H10F3NO3S2 |
| M. Wt | 409.4 |
| Purity | >98% |
| Synonyms | CFTR inhibitor 172 |
| SMILES | C1=CC(=CC(=C1)N2C(=O)/C(=C/C3=CC=C(C=C3)C(=O)O)/SC2=S)C(F)(F)F |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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