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CGP 29287

Catalog No.: A77517
Renin Inhibitor
CGP 29287 is a potent inhibitor of renin, the enzyme responsible for the conversion of angiotensinogen to angiotensin I in the renin-angiotensin system. By selectively inhibiting renin activity, CGP 29287 plays a critical role in studying the regulation of blood pressure and cardiovascular function. This compound is useful in research applications focusing on hypertension, heart failure, and related metabolic disorders.
CGP 29287 93287-54-8 Renin Inhibitor
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Size Price Stock Qty
25mg
$1,275.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCGP 29287 is a potent inhibitor of renin, the enzyme responsible for the conversion of angiotensinogen to angiotensin I in the renin-angiotensin system. By selectively inhibiting renin activity, CGP 29287 plays a critical role in studying the regulation of blood pressure and cardiovascular function. This compound is useful in research applications focusing on hypertension, heart failure, and related metabolic disorders.
Product Information
Catalog NumA77517
FormulaC72H110N20O15
Molecular Weight1495.77
CAS Number93287-54-8
Sequence{Z}-Arg-Arg-Pro-Phe-His-{Sta}-Ile-His-{Lys(Boc)}-{Ome}
Sequence shortening{Z}-RRPFH-{Sta}-IH-{Lys(Boc)}-{Ome}
SMILESC([C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)CCCNC(=N)N)=O)CCCNC(=N)N)(=O)N2[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CN=CN4)C(N[C@H]([C@H](CC(N[C@H](C(N[C@@H](CC5=CN=CN5)C(N[C@@H](CCCCNC(OC(C)(C)C)=O)C(OC)=O)=O)=O)[C@H](CC)C)=O)O)CC(C)C)=O)=O)=O)CCC2
SynonymsZ-Arg-Arg-Pro-Phe-His-Sta-Ile-His-Lys(Boc)-Ome
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

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Endocrinology-Hormones > renin-angiotensin-aldosterone system (RAAS)