CGP 57380 is an inhibitor of MAP-kinase interacting kinase-1 (Mnk1, MKNK1) (IC50 = 2.2 uM).
Targets
Target
Value
Cell Research
Cell Line
Type
Value
Description
References
Product Information
Catalog Num
A13883
Formula
C11H9FN6
Molecular Weight
244.23
CAS Number
522629-08-9
SMILES
C1=CC(=CC=C1NC2=C3C(=NC=NC3=NN2)N)F
Synonyms
CGP57380, CGP-57380
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro (25°C)
DMSO
Warmed: 43 mg/mL (176.06 mM)
Water
Insoluble
Ethanol
Insoluble
In vivo
4% DMSO+30% PEG 300+ddH2O
9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
