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$0.00 - Jie Tang, .et al. 2,2',4,4'-Tetrabromodiphenyl ether (BDE-47) activates Aryl hydrocarbon receptor (AhR) mediated ROS and NLRP3 inflammasome/p38 MAPK pathway inducing necrosis in cochlear hair cells, Ecotoxicol Environ Saf, 2021, Sep 15;221:112423 PMID: 34146985
Biological Activity
CH-223191 is a ligand-selective antagonist of the Ah (Dioxin) receptor.
Targets
| AhR | ||||
| 30 nM |
| In vitro | DMSO | 61 mg/mL (182.96 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 4 mg/mL (11.99 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.99 mL | 149.97 mL | 299.95 mL |
| 0.5 mM | 6 mL | 29.99 mL | 59.99 mL |
| 1 mM | 3 mL | 15 mL | 29.99 mL |
| 5 mM | 0.6 mL | 3 mL | 6 mL |
*The above data is based on the productmolecular weight 333.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15436 |
|---|---|
| Actions | Antagonist |
| CAS No. | 301326-22-7 |
| Formula | C19H19N5O |
| M. Wt | 333.39 |
| Purity | >98% |
| Synonyms | CH223191 |
| SMILES | CC1=CC=CC=C1N=NC2=CC(=C(C=C2)NC(=O)C3=CC=NN3C)C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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