CH4933468 is a thiohydantoin derivative that functions as a pure antagonist of the androgen receptor (AR). This compound effectively inhibits AR-mediated transactivation and suppresses the proliferation of LNCaP and LNCaP-BC2 cancer cell lines. CH4933468 is particularly relevant for research in castration-resistant prostate cancer (CRPC), providing a valuable tool for investigating therapeutic strategies in this context.
CH4933468 is a thiohydantoin derivative that functions as a pure antagonist of the androgen receptor (AR). This compound effectively inhibits AR-mediated transactivation and suppresses the proliferation of LNCaP and LNCaP-BC2 cancer cell lines. CH4933468 is particularly relevant for research in castration-resistant prostate cancer (CRPC), providing a valuable tool for investigating therapeutic strategies in this context.
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