CH5137291 is a potent pure antagonist of the androgen receptor (AR) that operates by preventing the translocation of AR from the cytoplasm to the nucleus, thereby inhibiting AR-mediated signaling. This compound demonstrates significant biological activity by completely suppressing tumor growth in both cell lines and mouse models of castration-resistant prostate cancer (CRPC). CH5137291 is a valuable tool for researchers investigating the mechanisms and therapeutic approaches related to CRPC.
CH5137291 is a potent pure antagonist of the androgen receptor (AR) that operates by preventing the translocation of AR from the cytoplasm to the nucleus, thereby inhibiting AR-mediated signaling. This compound demonstrates significant biological activity by completely suppressing tumor growth in both cell lines and mouse models of castration-resistant prostate cancer (CRPC). CH5137291 is a valuable tool for researchers investigating the mechanisms and therapeutic approaches related to CRPC.
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