Chalepensin is a furanocoumarin that acts as a competitive inhibitor of the cytochrome P450 enzyme CYP2A6. In addition to its primary inhibitory effects on CYP2A6, Chalepensin has been shown to inhibit several other CYP enzymes, including CYP1A1, CYP1A2, CYP2A13, CYP2C9, CYP2D6, CYP2E1, and CYP3A4, albeit to varying degrees. This compound is valuable for research into drug metabolism and enzyme regulation, as well as for studies on the pharmacokinetics of therapeutic agents that undergo cytochrome P450-mediated biotransformation.
Chalepensin is a furanocoumarin that acts as a competitive inhibitor of the cytochrome P450 enzyme CYP2A6. In addition to its primary inhibitory effects on CYP2A6, Chalepensin has been shown to inhibit several other CYP enzymes, including CYP1A1, CYP1A2, CYP2A13, CYP2C9, CYP2D6, CYP2E1, and CYP3A4, albeit to varying degrees. This compound is valuable for research into drug metabolism and enzyme regulation, as well as for studies on the pharmacokinetics of therapeutic agents that undergo cytochrome P450-mediated biotransformation.
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