Chimaphilin

Catalog No.: A12031

Chimaphilin

Chimaphilin Chemical Structure

CAS NO. 482-70-2

Chimaphilin is extracted from pyrola [Passiflora incarnata Fisch.] Chimaphilin could inhibit the viability of MCF-7 cells in a concentration-dependent manner, and the IC50 value was 43.30μM for 24h.

Availability: Out of stock

Package Price
50 mg
$120.00
100 mg
$200.00
250 mg
$400.00
500 mg
$700.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Dong F, .et al. Chimaphilin inhibits human osteosarcoma cell invasion and metastasis through suppressing the TGF-β1-induced epithelial-to-mesenchymal transition markers via PI-3K/Akt, ERK1/2, and Smad signaling pathways, Can J Physiol Pharmacol, 2018, Jan;96(1):1-7 PMID: 28177668
  • Wan Daqian, .et al. Chimaphilin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell lines through insulin-like growth factor-I receptor (IGF-IR) signaling., Chem Biol Interact., 2015, Jul 25;237:25-30 PMID: 25980584

Biological Activity

Chimaphilin is extracted from pyrola [Passiflora incarnata Fisch.] Chimaphilin could inhibit the viability of MCF-7 cells in a concentration-dependent manner, and the IC50 value was 43.30μM for 24h.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 53.7 mL 268.51 mL 537.03 mL
0.5 mM 10.74 mL 53.7 mL 107.41 mL
1 mM 5.37 mL 26.85 mL 53.7 mL
5 mM 1.07 mL 5.37 mL 10.74 mL

*The above data is based on the productmolecular weight 186.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12031
CAS No. 482-70-2
Formula C12H10O2
M. Wt 186.21
Purity >98%
SMILES CC1=CC2=C(C=C1)C(=O)C=C(C2=O)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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