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Chlorahololide C

Catalog No.: A68086
Potassium Channel Blocker
Chlorahololide C is a lindenane sesquiterpenoid dimer that acts as a potent and selective blocker of potassium channels, exhibiting an IC50 value of 3.6 μM. This compound is derived from Chloranthus holostegius and is valuable for research into potassium channel function and related signaling pathways. Its selective inhibition makes it a useful tool for investigating the role of potassium channels in physiological and pathological processes.
Chlorahololide C 1007859-25-7 Potassium Channel Blocker
Grouped product items
Size Price Stock Qty
1mg
$385.00
In stock
5mg
$580.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionChlorahololide C is a lindenane sesquiterpenoid dimer that acts as a potent and selective blocker of potassium channels, exhibiting an IC50 value of 3.6 μM. This compound is derived from Chloranthus holostegius and is valuable for research into potassium channel function and related signaling pathways. Its selective inhibition makes it a useful tool for investigating the role of potassium channels in physiological and pathological processes.
Product Information
Catalog NumA68086
FormulaC33H36O9
Molecular Weight576.63
CAS Number1007859-25-7
SMILESCOC(/C(C)=C1C2=C([C@]([C@@]3([H])[C@]4([H])C3)([C@H](C/1=O)O)C)[C@]4(O)C[C@]([C@@]5([C@@](C([C@]6([H])[C@@]5([H])C6)=C)([H])[C@H]7OC(C)=O)C)([H])[C@@]28C7=C(C(O8)=O)C)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Membrane Transporters-Ion Channels > Potassium Channels