Fig. 1 · Structure
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Chloroquine-d5 diphosphate
Stable Isotope
Chloroquine-d5 diphosphate is a deuterium-labeled form of Chloroquine, functioning as a stable isotope. This compound exhibits potent antimalarial and anti-inflammatory properties, making it relevant for research in malaria treatment and rheumatoid arthritis. Additionally, Chloroquine-d5 diphosphate acts as an inhibitor of autophagy and toll-like receptors (TLRs), and has shown significant efficacy against SARS-CoV-2 in vitro, aiding studies in viral infection mechanisms and therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1854126-42-3 |
| Applications | Stable Isotope |
| Formula | C18H27D5ClN3O8P2 |
| Molecular Weight | 520.89 |
| SMILES | CC(NC1=CC=NC2=CC(Cl)=CC=C12)CCCN(CC)C([2H])([2H])C([2H])([2H])[2H].O=P(O)(O)O.O=P(O)(O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.