Chlorphenoxamine hydrochloride

Catalog No.: A33949
Antihistamine/anticholinergic Agent
Chlorphenoxamine hydrochloride is an antihistamine and anticholinergic agent that functions as a GPCR antagonist. It exhibits potent antiviral activity against lethal viral pathogens, including SARS-CoV, MERS-CoV, and Ebola virus, with reported IC50 values of 1.1 μM against Ebola virus and 6.2 μM against Marburg virus. This compound is utilized in research related to allergic conditions, urticaria, viral infections, and the treatment of Parkinson’s disease.
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5mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionChlorphenoxamine hydrochloride is an antihistamine and anticholinergic agent that functions as a GPCR antagonist. It exhibits potent antiviral activity against lethal viral pathogens, including SARS-CoV, MERS-CoV, and Ebola virus, with reported IC50 values of 1.1 μM against Ebola virus and 6.2 μM against Marburg virus. This compound is utilized in research related to allergic conditions, urticaria, viral infections, and the treatment of Parkinson’s disease.
Product Information
Catalog NumA33949
FormulaC18H23Cl2NO
Molecular Weight340.29
CAS Number562-09-4
SMILESCC(C1=CC=CC=C1)(C2=CC=C(Cl)C=C2)OCCN(C)C.Cl
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