CHMFL-EGFR-202

Catalog No.: A12524

EGFR inhibitor

CHMFL-EGFR-202

CHMFL-EGFR-202 Chemical Structure

CAS NO. 2089381-40-6

CHMFL-EGFR-202 is a potent, irreversible inhibitor of epidermal growth factor receptor (EGFR) mutant kinase, with IC50s of 5.3 nM and 8.3 nM for drug-resistant mutant EGFR T790M and WT EGFR kinases, respectively.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

CHMFL-EGFR-202 is a potent, irreversible inhibitor of epidermal growth factor receptor (EGFR) mutant kinase, with IC50s of 5.3 nM and 8.3 nM for drug-resistant mutant EGFR T790M and WT EGFR kinases, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.41 mL 102.05 mL 204.1 mL
0.5 mM 4.08 mL 20.41 mL 40.82 mL
1 mM 2.04 mL 10.2 mL 20.41 mL
5 mM 0.41 mL 2.04 mL 4.08 mL

*The above data is based on the productmolecular weight 489.96. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12524
Actions Inhibitor
M. Wt 489.96
Formula C25H24ClN7O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2089381-40-6
SMILES O=C(N(C1)CCC[[email protected]]1N2C3=NC=NC(N)=C3C(C4=CC(Cl)=C(OCC5=NC=CC=C5)C=C4)=N2)C=C

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